The purpose of the recent study was to determine the heavy metals (Pb, Zn, Cd and Ni) content in samples of medicinal plants collected from Batak Municipality by the application of microwave system Mileston 1200 MEGA for sample preparation. ICP – OES was used for the quantity determination of the heavy metals. Certified Virginia Tobacco CTA-VTL-2 material was applied to test the analyses accuracy. The analytical results obtained displayed that the concentrations of the metals determined were below the permissible levels regulated by the World Health Organization. It was established that due to the considerably reduced acid consumption and analyses time, microwave mineralization could be accepted as the most economically profitable sample preparation method.